A Comparative Study of Perfusion Measurement in Brain Tumours at 3 Tesla MR : Arterial Spin Labeling versus Dynamic Susceptibility Contrast-Enhanced MRI
Résumé
PURPOSE: To prove the feasibility of arterial spin labeling (ASL) to explore brain tumors by comparing dynamic susceptibility contrast-enhanced MRI to ASL at 3T MR.
MATERIALS AND METHODS: Twenty-seven patients were included presenting 9 gliomas, 10 metastases and 8 meningiomas. All were explored by a pseudo-continuous ASL and dynamic susceptibility contrast-enhanced T2* perfusion sequence. Two neuroradiologists analyzed the cerebral blood flow (CBF) maps to assess feasibility, examination quality and quantitative comparison. The Spearman nonparametric correlation test and the Bland-Altman graphic test were used to analyze our quantitative results.
RESULTS: 92% of ASL CBF maps were informative. ASL detected all lesions as well as dynamic susceptibility contrast-enhanced MRI. Both sequences provide relative quantitative CBF values closely correlated.
CONCLUSION: On a 3T MR unit, ASL is a good alternative to dynamic susceptibility contrast-enhanced MRI when contrast medium is contraindicated or intravenous injection is not possible. Its results on relative CBF parameters are similar to contrast-injected perfusion.
Fichier principal
Lehmann-Petal._A-comparative-study-of-perfusion-measurement-in-brain-tumours-at-3-.pdf (245.3 Ko)
Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)
Loading...