, Global status report on noncommunicable diseases, 2014.

V. L. Roger, A. S. Go, D. M. Lloyd-jones, R. J. Adams, J. D. Berry et al., Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics, vol.123, 2011.

M. Nichols, N. Townsend, P. Scarborough, and M. Rayner, Cardiovascular disease in Europe 2014: epidemiological update, Eur Heart J, vol.35, p.2929, 2014.

, World Health Organization. Cardiovascular diseases (CVDs). World health organization, 2015.

A. K. Chomistek, J. E. Manson, M. L. Stefanick, B. Lu, M. Sands-lincoln et al., Relationship of sedentary behavior and physical activity to incident cardiovascular disease: results from the Women' s Health Initiative, J Am Coll Cardiol, vol.61, pp.2346-2354, 2013.

C. P. Wen and X. Wu, Stressing harms of physical inactivity to promote exercise, Lancet, vol.380, pp.192-193, 2012.

S. Yusuf, S. Hawken, S. Ounpuu, T. Dans, A. Avezum et al., Lisheng L; INTERHEART Study Investigators. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study, Lancet, vol.364, pp.937-952, 2004.

C. Kim and G. L. Beckles, Cardiovascular disease risk reduction in the Behavioral Risk Factor Surveillance System, Am J Prev Med, vol.27, pp.1-7, 2004.

J. Li and J. Siegrist, Physical activity and risk of cardiovascular disease--a meta-analysis of prospective cohort studies, Int J Environ Res Public Health, vol.9, pp.391-407, 2012.

N. L. Glazer, A. Lyass, D. W. Esliger, S. J. Blease, P. S. Freedson et al., Sustained and shorter bouts of physical activity are related to cardiovascular health, Med Sci Sports Exerc, vol.45, pp.109-115, 2013.

G. Musumeci, Effects of exercise on physical limitations and fatigue in rheumatic diseases, World J Orthop, vol.6, pp.762-769, 2015.

G. Musumeci, C. Loreto, R. Imbesi, F. M. Trovato, D. Giunta et al., Advantages of exercise in rehabilitation, treatment and prevention of altered morphological features in knee osteoarthritis. A narrative review, Histol Histopathol, vol.29, pp.707-719, 2014.

A. S. Fairey, K. S. Courneya, C. J. Field, and J. R. Mackey, Physical exercise and immune system function in cancer survivors: a comprehensive review and future directions, Cancer, vol.94, pp.539-551, 2002.

K. O'brien, S. Nixon, A. M. Tynan, and R. Glazier, Aerobic exercise interventions for adults living with HIV/AIDS. Cochrane Database Syst Rev, p.1796, 2010.

L. Anderson and R. S. Taylor, Cardiac rehabilitation for people with heart disease: an overview of Cochrane systematic reviews, Cochrane Database Syst Rev, 2014.

R. S. Taylor, A. Brown, S. Ebrahim, J. Jolliffe, H. Noorani et al., Exercise-based rehabilitation for patients with coronary heart disease: systematic review and meta-analysis of randomized controlled trials, Am J Med, vol.116, pp.682-692, 2004.

D. G. Simons-morton, K. J. Calfas, B. Oldenburg, and N. W. Burton, Effects of interventions in health care settings on physical activity or cardiorespiratory fitness, Am J Prev Med, vol.15, pp.413-430, 1998.

M. F. Piepoli, U. Corrà, W. Benzer, B. Bjarnason-wehrens, P. Dendale et al., Cardiac Rehabilitation Section of the European Association of Cardiovascular Prevention and Rehabilitation. Secondary prevention through cardiac rehabilitation: from knowledge to implementation. A position paper from the Cardiac Rehabilitation Section of the European Association of Cardiovascular Prevention and Rehabilitation, Eur J Cardiovasc Prev Rehabil, vol.17, pp.1-17, 2010.

P. Kokkinos, Physical activity, health benefits, and mortality risk, ISRN Cardiol, vol.2012, p.718789, 2012.

M. Guazzi, V. Adams, V. Conraads, M. Halle, A. Mezzani et al., European Association for Cardiovascular Prevention & Rehabilitation

, EACPR/AHA Scientific Statement. Clinical recommendations for cardiopulmonary exercise testing data assessment in specific patient populations, American Heart Association, vol.126, pp.2261-2274, 2012.

J. E. Hansen, D. Y. Sue, and K. Wasserman, Predicted values for clinical exercise testing, Am Rev Respir Dis, vol.129, pp.49-55, 1984.

K. Wasserman, J. E. Hansen, D. Y. Sue, W. Stringer, and B. J. Whipp, Principles of Exercise Testing and Interpretation, pp.160-182, 2005.

, European Society of HypertensionEuropean Society of Cardiology guidelines for the management of arterial hypertension, J Hypertens, vol.21, pp.1011-1053, 2003.

S. C. Smith, S. N. Blair, R. O. Bonow, L. M. Brass, M. D. Cerqueira et al., AHA/ACC Scientific Statement: AHA/ACC guidelines for preventing heart attack and death in patients with atherosclerotic cardiovascular disease: 2001 update: A statement for healthcare professionals from the American Heart Association and the American College of Cardiology, Circulation, vol.104, pp.1577-1579, 2001.

P. M. Gargiullo, R. B. Rothenberg, and H. G. Wilson, Confidence intervals, hypothesis tests, and sample sizes for the prevented fraction in crosssectional studies, Stat Med, vol.14, pp.51-72, 1995.

O. S. Miettinen, Proportion of disease caused or prevented by a given exposure, trait or intervention, Am J Epidemiol, vol.99, pp.325-332, 1974.

S. N. Blair, Y. Cheng, and J. S. Holder, Is physical activity or physical fitness more important in defining health benefits?, Med Sci Sports Exerc, vol.33, pp.379-99, 2001.

J. Myers, M. Prakash, V. Froelicher, D. Do, S. Partington et al., Exercise capacity and mortality among men referred for exercise testing, N Engl J Med, vol.346, pp.793-801, 2002.

C. J. Lavie, R. Arena, D. L. Swift, N. M. Johannsen, X. Sui et al., Exercise and the cardiovascular system: clinical science and cardiovascular outcomes, Circ Res, vol.117, pp.207-219, 2015.

M. E. Mccusker, P. W. Yoon, M. Gwinn, A. M. Malarcher, L. Neff et al., Family history of heart disease and cardiovascular disease risk-reducing behaviors, Genet Med, vol.6, pp.153-158, 2004.

A. Bernardo, R. C. Rossi, S. Nmd, C. M. Pastre, and L. Vanderlei, Association between physical activity and cardiovascular risk factors in individuals undergoing cardiac rehabilitation program, Revista Brasileira de Medicina do Esporte, p.231, 2013.

A. Ko?tuniuk and J. Rosi?czuk, The prevalence of risk factors for cardiovascular diseases among Polish surgical patients over 65 years, Clin Interv Aging, vol.11, pp.631-639, 2016.

L. Sandvik, J. Erikssen, E. Thaulow, G. Erikssen, R. Mundal et al., Physical fitness as a predictor of mortality among healthy, middleaged Norwegian men, N Engl J Med, vol.328, pp.533-537, 1993.

J. L. Fleg, C. H. Morrell, A. G. Bos, L. J. Brant, L. A. Talbot et al., Accelerated longitudinal decline of aerobic capacity in healthy older adults, Circulation, vol.112, pp.674-682, 2005.

S. Kodama, K. Saito, S. Tanaka, M. Maki, Y. Yachi et al., Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women: a meta-analysis, JAMA, vol.301, pp.2024-2035, 2009.

L. S. Pescatello, B. A. Franklin, R. Fagard, W. B. Farquhar, G. A. Kelley et al., American College of Sports Medicine position stand. Exercise and hypertension, Med Sci Sports Exerc, vol.36, pp.533-553, 2004.

D. C. Lee, X. Sui, T. S. Church, C. J. Lavie, A. S. Jackson et al., Changes in fitness and fatness on the development of cardiovascular disease risk factors hypertension, metabolic syndrome, and hypercholesterolemia, J Am Coll Cardiol, vol.59, pp.665-672, 2012.

K. R. Sahakyan, V. K. Somers, J. P. Rodriguez-escudero, D. O. Hodge, R. E. Carter et al., Normal-Weight Central Obesity: Implications for Total and Cardiovascular Mortality, Ann Intern Med, vol.163, pp.827-835, 2015.

C. J. Lavie, P. A. Mcauley, T. S. Church, R. V. Milani, and S. N. Blair, Obesity and cardiovascular diseases: implications regarding fitness, fatness, and severity in the obesity paradox, J Am Coll Cardiol, vol.63, pp.1345-1354, 2014.

G. Hu, J. Eriksson, N. C. Barengo, T. A. Lakka, T. T. Valle et al., Occupational, commuting, and leisuretime physical activity in relation to total and cardiovascular mortality among Finnish subjects with type 2 diabetes, Circulation, vol.110, pp.666-673, 2004.

B. J. Nicklas, L. I. Katzel, L. B. Bunyard, K. E. Dennis, and A. P. Goldberg, Effects of an American Heart Association diet and weight loss on lipoprotein lipids in obese, postmenopausal women, Am J Clin Nutr, vol.66, pp.853-859, 1997.

H. E. Resnick, P. Valsania, J. B. Halter, and X. Lin, Relation of weight gain and weight loss on subsequent diabetes risk in overweight adults, J Epidemiol Community Health, vol.54, pp.596-602, 2000.

K. Suija, M. Timonen, M. Suviola, J. Jokelainen, M. R. Järvelin et al., The association between physical fitness and depressive symptoms among young adults: results of the Northern Finland 1966 birth cohort study, BMC Public Health, vol.13, p.535, 2013.

J. Barth, M. Schumacher, and C. Herrmann-lingen, Depression as a risk factor for mortality in patients with coronary heart disease: a metaanalysis, Psychosom Med, vol.66, 2004.

J. P. Bounhoure, M. Galinier, D. Curnier, M. Bousquet, and A. Bes,

, Bull Acad Natl Med, vol.190, pp.1731-1732, 2006.

R. A. Gary, S. B. Dunbar, M. K. Higgins, D. L. Musselman, and A. L. Smith, Combined exercise and cognitive behavioral therapy improves outcomes in patients with heart failure, J Psychosom Res, vol.69, pp.119-131, 2010.

M. Armero, A. , C. Hernandez, M. A. Perez-vicente, S. Martinez-martinez et al., Pharmaceutical care in smoking cessation, Patient Prefer Adherence, vol.9, pp.209-215, 2015.

D. H. Mouhamed, A. Ezzaher, F. Neffati, L. Gaha, W. Douki et al., Association between cigarette smoking and dyslipidemia. Immunoanalyse Biologie Spécialisée, p.195, 2013.

N. B. Oldridge, G. H. Guyatt, M. E. Fischer, and A. A. Rimm, Cardiac rehabilitation after myocardial infarction. Combined experience of randomized clinical trials, JAMA, vol.260, pp.945-950, 1988.

G. T. O'connor, J. E. Buring, S. Yusuf, S. Z. Goldhaber, E. M. Olmstead et al., An overview of randomized trials of rehabilitation with exercise after myocardial infarction, Circulation, vol.80, pp.234-244, 1989.

C. Bouchard and T. Shepard, Physical activity, fitness and health the model and key concepts ln C Bouchard, pp.11-23, 1993.

P. D. Thompson, R. Arena, D. Riebe, and L. S. Pescatello, ACSM's new preparticipation health screening recommendations from ACSM's guidelines for exercise testing and prescription, Curr Sports Med Rep, vol.12, pp.215-217, 2013.

M. Guazzi, R. Arena, M. Halle, M. F. Piepoli, J. Myers et al., Focused Update: Clinical Recommendations for Cardiopulmonary Exercise Testing Data Assessment in Specific Patient Populations, Circulation, vol.133, pp.694-711, 2016.